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LOS ANGELES - The powerful sedative Diprivan was found in Michael Jackson's home, a law enforcement official said Friday.
Diprivan is an anesthetic widely used in operating rooms to induce unconsciousness. Also known as Propofol, it's administered intravenously and is very unusual to have in a private home.
The law enforcement official spoke on condition of anonymity because the person was not authorized to speak about the matter.
Also Thursday, information was released about registering for free tickets for Jackson's public memorial, which is set for Tuesday at the Staples Center in Los Angeles.
Authorities are investigating allegations that the 50-year-old Jackson had been consuming painkillers, sedatives and antidepressants. Any criminal charges would depend on whether Jackson had been overly prescribed medications, given drugs inappropriate for his needs, or if doctors knowingly prescribed Jackson medications under an assumed name.
As Jackson recently prepared for a massive series of comeback concerts, he was so distraught over persistent insomnia that he pleaded for Diprivan, according to Cherilyn Lee, a registered nurse who was working with the singer.
Lee said she repeatedly rejected his demands because the drug was unsafe.
It's still not known what caused Jackson's death at age 50. The pop star went into cardiac arrest in his bedroom and his personal physician, Dr. Conrad Murray, performed CPR while an ambulance was called, according to Murray's lawyers. Murray has spoken to police and authorities say he is not a suspect.
An autopsy was conducted but results are not expected for several weeks. The Jackson family had a second autopsy performed and those results also are pending.
Free tickets to Jackson's memorial service can be obtained by registering at Staplescenter.com
There will be 11,000 tickets for seats inside Staples Center and 6,500 for seats in the adjacent Nokia Theatre, where fans can watch a simulcast. There also will be a free worldwide video feed.
After 6 p.m. Saturday, 8,750 names will be randomly selected to receive two tickets each. Notifications will go out on Sunday. Those selected can obtain their tickets via Ticketmaster on Monday.
No details of the memorial service itself have been released.
Former Jackson Nurse States Michael Begged Her For Diprivan
LOS ANGELES - Michael Jackson was so distraught over persistent insomnia in recent months that he pleaded for a powerful sedative despite warnings it could be harmful, says a nutritionist who was working with the singer as he prepared his comeback bid.
Cherilyn Lee, a registered nurse whose specialty includes nutritional counseling, said Tuesday that she repeatedly rejected his demands for the drug, Diprivan, which is given intravenously.
But a frantic phone call she received from Jackson four days before his death made her fear that he somehow obtained Diprivan or another drug to induce sleep, Lee said.
While in Florida on June 21, Lee was contacted by a member of Jackson's staff.
"He called and was very frantic and said, `Michael needs to see you right away.' I said, 'What's wrong?' And I could hear Michael in the background ..., 'One side of my body is hot, it's hot, and one side of my body is cold. It's very cold,'" Lee said.
"I said, `Tell him he needs to go the hospital. I don't know what's going on, but he needs to go to the hospital ... right away."
"At that point I knew that somebody had given him something that hit the central nervous system," she said, adding, "He was in trouble Sunday and he was crying out."
Jackson did not go to the hospital. He died June 25 after suffering cardiac arrest, his family said. Autopsies have been conducted, but an official cause of death is not expected for several weeks.
"I don't know what happened there. The only thing I can say is he was adamant about this drug," Lee said.
Nurse: Jackson desperate for sleep:
Following Jackson's death, allegations emerged that the 50-year-old King of Pop had been consuming painkillers, sedatives and antidepressants. But Lee said she encountered a man tortured by sleep deprivation and one who expressed opposition to recreational drug use.
"He wasn't looking to get high or feel good and sedated from drugs," she said. "This was a person who was not on drugs. This was a person who was seeking help, desperately, to get some sleep, to get some rest."
Jackson was rehearsing hard for what would have been his big comeback — his "This Is It" tour, a series of performances that would have strained his aging dancer's body. Also, pain had been a part of his life since 1984, when his scalp was severely burned during a Pepsi commercial shoot.
Several months ago, Jackson had begun badgering Lee about Diprivan, also known as Propofol, Lee said. It is an intravenous anesthetic drug widely used in operating rooms to induce unconsciousness. It is generally given through an IV needle in the hand.
Patients given Propofol take less time to regain consciousness than those administered certain other drugs, and they report waking up more clear-headed and refreshed, said University of Chicago psychopharmacologist James Zacny.
It has also been implicated in drug abuse, with people using it to "chill out" or to commit suicide, Zacny said. Accidental deaths linked to abuse have been reported. The powerful drug has a very narrow therapeutic window, meaning it doesn't take doses much larger than the medically recommended amount to stop a person's breathing.
An overdose that stops breathing can result in a buildup of carbon dioxide, causing the heart to beat erratically and leading to cardiac arrest, said Dr. John Dombrowski, a member of the board of directors of the American Society of Anesthesiologists.
Because it is given intravenously and is not the kind of prescription drug typically available from pharmacists, abuse cases have involved anesthesiologists, nurses and other hospital staffers with easy access to the drug, Zacny said.
In recent months, Lee said, Jackson waved away her warnings about it.
"I had an IV and when it hit my vein, I was sleeping. That's what I want," Lee said Jackson told her.
"I said, 'Michael, the only problem with you taking this medication' — and I had a chill in my body and tears in my eyes three months ago — 'the only problem is you're going to take it and you're not going to wake up," she recalled.
According to Lee, Jackson said it had been given to him before but he didn't want to discuss the circumstances or identify the doctor involved.
The singer also drew his own distinctions when it came to drugs versus prescription medicine.
"He said, `I don't like drugs. I don't want any drugs. My doctor told me this is a safe medicine,'" Lee said. The next day, she said she brought a copy of the Physician's Desk Reference to show him the section on Diprivan.
"He said, 'No, my doctor said it's safe. It works quick and it's safe as long as somebody's here to monitor me and wake me up. It's going be OK,'" Lee said. She said he did not give the doctor's name.
Lee said at one point, she spent the night with Jackson to monitor him while he slept. She said she gave him herbal remedies and stayed in a corner chair in his vast bedroom.
After he settled in bed, Lee told Jackson to turn down the lights and music — he had classical music playing in the house. "He also had a computer on the bed because he loved Walt Disney," she said. "He was watching Donald Duck and it was ongoing. I said, `Maybe if we put on softer music,' and he said, `No, this is how I go to sleep.'"
Three and a half hours later, Jackson jumped up and looked at Lee, eyes wide open, according to Lee. "This is what happens to me," she quoted him as saying. "All I want is to be able to sleep. I want to be able to sleep eight hours. I know I'll feel better the next day."
Did insomnia have roots in 2005 trial?
Lee, 56, is licensed as a registered nurse and nurse practitioner in California, according to the state Board of Registered Nursing's Web site. She attended Los Angeles Southwest College and the Charles Drew University of Medicine and Sciences in Los Angeles.
Comedian Dick Gregory, who knows Lee and her work, said he believes Jackson's insomnia had its roots in the pop star's 2005 trial on child molestation charges. Jackson's health had deteriorated so much that his parents called Gregory, a natural foods proponent, for help.
Gregory said Jackson wasn't eating or drinking at the time, and after he was persuaded by Gregory to undergo testing, ended up hospitalized for severe dehydration.
But Jackson obviously was healthy enough to withstand the level of medical scrutiny needed to insure him for the upcoming high-stakes London concerts, Gregory said. "That you don't trick," he said of the exams.
Lee, who has also worked with Stevie Wonder, Marla Gibbs, Reynaldo Rey and other celebrities, said she was introduced to Jackson by the mother of one of his staff members. Jackson's three children had minor cold symptoms and their pediatrician was out of town.
Lee said she went to the house in January, the first of about 10 visits there through April, and treated the children with vitamins. Michael, intrigued, asked what else she did and took her up on her claim she could boost his energy.
After running blood tests, she devised protein shakes for him and gave him an intravenous vitamin and mineral mixture — known as a "Myers cocktail," after Dr. John Myers — which Lee said she uses routinely in her practice.
"It wasn't that he felt sick," she said. "He just wanted more energy."
Lee said she decided to speak out to protect Jackson's reputation from what she considers unfounded allegations of drug abuse or shortcomings as a parent.
"I think it's so wrong for people to say these things about him," she said. "He was a wonderful, loving father who wanted the best for his children."
What is Diprivan?
Diprivan is used to start or maintain anesthesia during certain surgeries, tests, or procedures. It may also be used for other conditions as determined by your doctor.
Diprivan is a general anesthetic. It is unknown exactly how this medication works.
Do NOT use this medication if:
* you are allergic to any ingredient in this medication
* you are allergic to eggs, egg products, soybeans, or soy products
Contact your doctor or health care provider right away if any of these apply to you.
Before using Diprivan :
Some medical conditions may interact with this medication . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
* if you are pregnant, planning to become pregnant, or are breast-feeding
* if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
* if you have allergies to medicines, foods, or other substances
* if you have inflammation of the pancreas, high lipid levels in the blood, or epilepsy
Some MEDICINES MAY INTERACT with this medication . Tell your health care provider if you are taking any other medicines, especially any of the following:
* Benzodiazepines (eg, alprazolam), narcotic pain relievers (eg, morphine), or other sedatives (eg, chloral hydrate) because they may increase the risk of this medication 's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if this medication may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
View Larger MapSources: MSN Music News, MSNBC, ABC News, Drugs.com, Dr Naps.com, Google Maps
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